|本期目录/Table of Contents|

[1]刘欢,李立青△,李学敏,等.离体猪胸主动脉的热传导率测试及分析*[J].生物医学工程研究,2017,01:17-22.
　LIU Huan,LI Liqing,LI Xuemin,et al.Measurement and Analysis of the Thermal Conductivity of Porcine Thoracic Aortain Vitro[J].Journal of Biomedical Engineering Research,2017,01:17-22.
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离体猪胸主动脉的热传导率测试及分析*(PDF)

《生物医学工程研究》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2017年01期
页码:
17-22
栏目:
出版日期:
2017-03-25

文章信息/Info

Title:
Measurement and Analysis of the Thermal Conductivity of Porcine Thoracic Aortain Vitro
文章编号:
1672-6278 (2017)01-0017-06
作者:
刘欢; 李立青△; 李学敏; 黄振华
哈尔滨工业大学机电工程学院，黑龙江 哈尔滨 150001
Author(s):
LIU Huan;  LI Liqing;  LI Xuemin;  HUANG Zhenhua
School of Mechatronics Engineering, Harbin Institute of Technology, Harbin 150001，Heilongjiang，China
关键词:
电外科; 血管闭合; 热损伤; 准稳态平板法; 热物性参数; 猪胸主动脉; 热传导率; 生物阻抗
Keywords:
Electrosurgery; Vessel sealing; Thermal damage; The quasi-steady state plate method; Thermo-physical parameters; Porcine thoracic aorta; Thermal conductivity; Bioelectrical impedance
分类号:
R318
DOI:
10.19529/j.cnki.1672-6278.2017.01.04
文献标识码:
A
摘要:
为进一步丰富血管组织热物性参数数据，以降低双极电外科血管闭合手术中高频电流产生的热量对手术装置加热点临近组织的热损伤，本研究基于准稳态平板法实验原理，采用电热膜和微型NTC热敏电阻分别作为加热元件和测温元件搭建实验装置;然后以家猪离体主动脉为研究对象，利用给电热膜通电加热组织、热敏电阻采集其温度数据，通过实验得到其热传导率数据；最后对比了血管组织热传导率和生物组织阻抗随温度变化特性。研究结果显示离体家猪胸主动脉在26.5℃时，热传导率为0.4150 W/m-K。在温度升高至63℃时之前，热传导率增加随温度升高变化不明显；当温度高于63℃之后，热传导率呈下降趋势；当温度高于79℃后，随温度的上升，因组织内含水量持续减少，血管组织热传导率随温度升高而快速下降，温度接近90℃时，热传导率下降到0.201 W/m-K。研究发现家猪主动脉热传导率的变化特性与生物组织阻抗随温度变化特性在温度区间非常吻合，表明组织热传导率和阻抗特性存在一定相关性，为深入揭示电外科手术过程中生物传热机理提供重要参考。
Abstract:
In order to further enrich the vascular tissue thermo-physical parameters data, and in the meanwhile, for the purpose of reducing the thermal damage of the surgical device on its adjacent tissues during bipolar electrosurgical operation that heat is generated by the high-frequency current flow through vessel tissue. Based on the principle of the quasi-steady plate method,the experimental device with an electro-thermal membrane and NTC thermistors used as the heating element and temperature measuring element,respectively, was set up firstly; then in-vitro porcine thoracic aorta tissue was taken as investigated subject to study its thermal conductivity with tissue heating using electric heating film and temperature acquisition using thermistor; finally, the comparison of tissue thermal conductivity and biological tissue impedance versus temperature was conducted. The experimental results showed that the thermal conductivity of porcine thoracic aorta was 0.415 W/m-K at 26.5℃.Before the temperature increased to 63℃, the incresmental alteration of thermal conductivity was not obvious with the increasing of temperature; when the temperature was higher than 63℃ the thermal conductivity presented a decreased trend; when the temperature was higher than 79℃ and less than 90℃, tissue thermal conductivity declined rapidly with temperature increasing due to the decreasing of the water content in the tissue, and the thermal conductivity decreased to 0.201 W/m K nearby 90℃. It is found that the performance of the thermal conductivity versus temperature fits with the performance of the biological tissue impedance versus temperature. These results demonstrate it may exist relevance between tissue thermal conductivity and its impedance, which can provide an important reference for further exploring the mechanism of bio-heat transfer in the process of electrosurgical surgery.

参考文献/References

备注/Memo

备注/Memo:
(收稿日期：2016-10-13) 国家自然科学基金资助项目（51075091）；中央高校基础研究基金资助项目（HIT.IBRSEM.201323）△通信作者Email:liliqing@hit.edu.cn
更新日期/Last Update: 2017-04-26