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[1]王惠敏,黄丹飞△,邹彤,等.基于双旋转波片法的癌变组织穆勒矩阵的测量研究*[J].生物医学工程研究,2018,02:148-152.
 WANG Huimin,HUANG Danfei,ZOU Tong,et al.Research on Mueller matrix measurement of cancerous tissue based on double rotating retarders[J].Journal of Biomedical Engineering Research,2018,02:148-152.
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基于双旋转波片法的癌变组织穆勒矩阵的测量研究*(PDF)

《生物医学工程研究》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2018年02期
页码:
148-152
栏目:
出版日期:
2018-06-25

文章信息/Info

Title:
Research on Mueller matrix measurement of cancerous tissue based on double rotating retarders
文章编号:
1672-6278 (2018)02-0148 -05
作者:
王惠敏1黄丹飞1△邹彤1李世维1钟艾琦2王雄才2
1.长春理工大学生命科学技术学院,吉林 长春 130022;2.长春理工大学光电工程学院,吉林 长春 130022
Author(s):
WANG Huimin1 HUANG Danfei1 ZOU Tong1 LI Shiwei1 ZHONG Aiqi2WANG Xiongcai2
1. School of Life Science and Technology,Changchun University of Science and Technology, Changchun 130022, Jilin Province,China;2. Photoelectric Engineering College,Changchun University of Science and Technology, Changchun 130022
关键词:
偏振成像 穆勒矩阵 偏振特性 双旋转波片法 癌变组织
Keywords:
Polarization imaging Mueller matrix Polarization characteristic Double rotating retarders Cancerous tissue
分类号:
R318;Q-334
DOI:
10.19529/j.cnki.1672-6278.2018.02.06
文献标识码:
A
摘要:
偏振成像由于自身的优势能够有效改善普通光学成像的不足,尤其是穆勒矩阵图像包含了目标的所有偏振信息。本研究基于双旋转波片法原理,搭建了一套穆勒矩阵成像系统,利用组织背向散射光进行成像,测量癌症病理切片的穆勒矩阵,以探求偏振成像区分癌变和非癌变组织的能力。对目前全球高发的肝癌,肺癌和胃癌三种癌症组织切片分别进行穆勒矩阵测量,成像结果发现不同的像元表达的偏振信息不同,某些穆勒矩阵元中,癌变和非癌变区域的偏振信息差异明显,可以用来辅助辨别癌变与正常组织。穆勒矩阵偏振成像在生物医学研究中将会是一种有潜力的病理检测方法。
Abstract:
Polarization imaging can effectively compensate for the shortcomings of ordinary optical imaging due to its own advantages, especially the Mueller matrix image that contains all the polarization information of target. In this paper, a set of Mueller matrix imaging system was established based on the principle of double rotating retarders to explore the ability of polarization imaging to distinguish cancerous and non-cancerous tissues, which utilized tissue backscattered light to measure Mueller matrix of pathological slices. The Mueller matrices of liver cancer, lung cancer and gastric cancer were measured respectively. These three kinds of cancers were high incidence in the world. Experimental results showed that the polarization information expressed by each Mueller matrix element was not the same. And in some Mueller matrix elements, the polarization characteristic of cancerous and non-cancerous regions was significantly different, which could be used to help identify cancer and normal tissue. Mueller matrix polarization imaging will be a potential pathological detection method in biomedical research.

参考文献/References

备注/Memo

备注/Memo:
(收稿日期:2017-07-14) 国家“973”计划项目(613225)。△通信作者Email:huangd_f@163.com
更新日期/Last Update: 2018-07-20