文章摘要

文章信息/Info

作者:: 罗狄锋1; 2; 张帆1; 付涛1△; 韩生兰1; 吴锋3; 1.西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室，西安 710049；2.广东顺德西安交通大学研究院，广东佛山 528300；3西安交通大学医学院，西安 710061

Author(s):: LUO Difeng1; 2; ZHANG Fan1; FU Tao1; HAN Shenglan1; WU Feng3; 1.School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049，China; ?2.Guangdong Shunde Xi’an Jiaotong University Academy, Foshan 528300，Guangdong，China；3. College of Medicine, Xi’an Jiaotong University, Xi’an 710061

Keywords:: Stainless steel; TiO2; Sol-gel; Nitriding; Hemocompatibility; Plasma

摘要:: 以抛光316L不锈钢和溶胶-凝胶TiO2涂层试样为对照，研究了等离子体渗氮试样的结构和性能。对磨光的不锈钢片采用浸涂法进行涂覆TiO2膜层处理，对溅射清洗后的磨光不锈钢片进行氮化等离子处理。TiO2薄膜没有明显改变不锈钢基体的表面形貌，但含有宽约1 μm的细长裂纹，涂层试样还检测到马氏体衍射峰。等离子体渗氮试样较为粗糙，其表面仅检测到膨胀的奥氏体（S相）。与抛光和TiO2涂层试样相比，渗氮试样较为亲水（接触角约70o），表面能的极性分量很高（86%），与水、血液和纤维蛋白原的界面张力较小，与白蛋白的界面张力较大。动电位极化实验表明渗氮试样具有最好的耐蚀性。三种材料都满足医学植入物的溶血率要求（<5%），渗氮试样具有最好的抗血小板聚集功能。

Abstract:: The structure and properties of plasma nitrided 316L stainless steel were studied in comparison with the polished sample and the sol-gel TiO2 coated sample.The polished stainless steel sheet was treated with TiO2 coating by dip coating method, and the polished stainless steel sheet after sputtering was treated by nitriding plasma. The TiO2 film did not obviously change surface morphology of stainless steel substrate, but it had fine cracks with the width of about 1 μm. Martensite diffraction peaks were also detected for the coating sample. The plasma nitrided sample was rough, and only the expanded austenite (S phase) was detected at the surface. Compared with the polished and the TiO2 coated samples, the nitrided sample was more hydrophilic (contact angle ~70o), with the dominant polar component of surface energy (86%). The nitrided sample had lower interfacial tensions towards water, blood and fibrinogen, but larger one towards albumin. The potentiodynamic polarization test showed that the nitrided sample had the best corrosion resistance. The three materials meet the hemolysis requirement for medical implants (<5%), and the nitrided sample has the best anti-platelet aggregating function.