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Title:: Design methodology research of microwave ablation antenna based on finite element method

Author(s):: WANG Juan; ZHAO Jinzhe; MU Yongjie; JIN Xiaofei; QIAN Zhiyu; LI Weitao; Department of Biomedical Engineering, College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China

Keywords:: Microwave ablation; Cancer; Finite element; Bioceramics; Optimization

摘要:: 微波消融针的性能决定肿瘤微波消融术后的消融区域形态与大小，研制具有更大消融范围及材料性质更稳定的消融针具有临床应用价值。本研究采用有限元仿真方法，将具有良好生物相容性的氧化锆陶瓷作为消融针穿刺头，设定优化指标，仿真得出2.45 GHz微波频率下的消融针部件尺寸。结果表明，同轴电缆内导体延伸长度，穿刺头前、后端的长度组合为(10, 11, 4)、(11, 12, 4)、(16, 12, 8)、(18, 12, 8) mm时分别可达最优轴比，最小初始反射系数以及两组最大消融体积。该仿真方法能够定量描述不同部件结构下优化指标的差异，有效辅助消融针设计从而缩短设计周期。

Abstract:: The shape and size of ablation zone is determined by the characteristic of microwave ablation antenna. It is of significance for clinical application to develop the antenna with larger ablation volume as well as more stable material. The zirconia ceramics with a favorable biocompatibility was set as puncturable part of antenna in this paper, we swept the parametric dimensions of antenna with the 2.45 GHz microwave frequency and the finite element method was adopted in this study. The simulations demonstrated that the extended length of inner conductor, front and back of the puncturable part were (10, 11, 4), (11, 12, 4), (16, 12, 8), (18, 12, 8) mm, the antenna would bring the largest axial ratio, the lowest reflection coefficient and two groups of the largest ablation volume. This simulation method quantifies difference of optimization indicator in each structure which is beneficial to microwave antenna designing and shortens the design cycle.