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Title:: Study on the experiment law of microwave irradiation of pork adipose tissue

Author(s):: GAO Xiaohan; SU Runzhou; GU Hongyuan; College of Science,Northeast Forestry University,Harbin 150040,China

Keywords:: Bio-heating effectiveness; Microwave; The depth of heat penetration; Aadipose tissue; Mass loss rate

摘要:: 微波在生物组织中的传播特性及生物组织内温度分布的研究对医疗诊断和临床治疗具有重要意义。本研究以2 450 MHz频率的微波治疗仪作为发射装置，以猪肉腹部皮下脂肪组织为研究对象，通过控制辐照时间和功率两个变量，测量脂肪组织上表面温度、质量损失率及透热深度，观察脂肪组织表面的微观形态，探究影响猪肉腹部皮下脂肪组织质量和透热深度的因素。由模拟得到的温升曲线可知，增大辐照时间和辐照功率可促使脂肪组织上表面温度升高，质量损失率和透热深度也随之增加，当上表面温度达到41.8 ℃时，出现透热深度。分析可知，脂肪组织透热深度最高约达20.8 mm，由热传导方程验证温升曲线随时间的增加变化率逐渐变小的趋势。本研究结论可为微波热疗中温度的分布及浅表皮热疗提供理论支持。

Abstract:: The study of the propagation characteristics of microwave and the temperature distribution in biological tissue is of great significance for medical diagnosis and clinical treatment. We used the ATM-A with frequency of 2 450 MHz as the launcher, and took the subcutaneous adipose tissue of pork belly as the object of study. By controlling two variables of the irradiation time and power, measuring the surface temperature，mass loss rate and depth of heat penetration of adipose tissue, observing the micro-morphology of the adipose tissue surface, we explored the factors affecting the mass and the depth of heat penetration of adipose tissue. The temperature rise curve showed that increased the irradiation time and power could cause the surface temperature to rise, mass loss rate and the depth of heat penetration of the adipose tissue also increased. The biological tissue showed the depth of heat penetration when the surface temperature reached 41.8 ℃. According to analysis of experimental, the depth of heat penetration could reach up to about 20.8 mm. It was verified by the equation of heat conduction that the change rate of the temperature rise curve decreased with time increased gradually. The conclusions can provide theoretical support for temperature distribution and superficial epithelial hyperthermia in microwave hyperthermia.