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Title:: Numerical simulation of the therapeutic effect of stent implantation for intracranial aneurysm

Author(s):: JIN Rongbo; MUHETAER Kelimu; SHEN Chuanpeng; School of Mechanical Engineering, Xinjiang University, Urumqi 830046，China

Keywords:: Vascular stent; Intracranial aneurysm; Hemodynamics; Fluid-solid interaction; Wall shear stress

摘要:: 研究不同结构形状的血管支架用于治疗颅内动脉瘤后对血流动力学的影响。针对同一个体化颅内动脉瘤模型，设计了三种网丝截面相同、通透率近似相等、结构形状不同的支架。将这三种支架植入颅内动脉瘤模型，进行双向流固耦合数值模拟，分析血流速度、壁面切应力的变化情况。三种支架中，螺旋型支架对动脉瘤瘤腔内的血流旋涡改善效果最佳，对动脉瘤瘤颈和瘤顶部分较高的壁面切应力削弱也最明显；周期型支架的柔顺性优于其余两种类型的支架。螺旋型支架植入颅内动脉瘤的治疗效果最佳，但不适合几何形状复杂的血管，本研究也可为进一步优化支架结构提供依据。

Abstract:: To investigate the influence of different structural shape of vascular stents on the treatment of intracranial aneurysms on hemodynamics. Three kinds of stents were designed for the same individual intracranial aneurysm model with the same cross section, similar permeability and different structure. The three stents were implanted into the intracranial aneurysm model, and the two-way fluid-solid interaction numerical simulation was carried out to analyze the changes of blood flow velocity and wall shear stress. In the three kinds of stents, the spiral stent had the best effect on the improvement of the blood flow in the aneurysm cavity, and the wall shear stress of the aneurysm neck and the top part of the aneurysm was also the most obvious; the flexibility of the periodic scaffold was superior to the other two types of stents. Spiral stent is the best choice for the treatment of intracranial aneurysms, but it is not suitable for the blood vessels with complex geometry. The result can provide the basis for further optimization of the stent structure.