|本期目录/Table of Contents|

[1]王楠楠,冯继玲,王义亮△.冠状动脉分叉角度对血液流体力学及斑块形成分布的影响[J].生物医学工程研究,2018,03:291-296.
 WANG Nannan,FENG Jiling,WANG Yiliang.The effect of left coronary bifurcation angle on vascular fluid hemodynamics as well as plaque formation and distribution[J].Journal of Biomedical Engineering Research,2018,03:291-296.
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冠状动脉分叉角度对血液流体力学及斑块形成分布的影响(PDF)

《生物医学工程研究》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2018年03期
页码:
291-296
栏目:
出版日期:
2018-09-25

文章信息/Info

Title:
The effect of left coronary bifurcation angle on vascular fluid hemodynamics as well as plaque formation and distribution
文章编号:
1672-6278 (2018)03-0291-06
作者:
王楠楠冯继玲王义亮△
太原理工大学 机械工程学院,太原 030024
Author(s):
WANG NannanFENG JilingWANG Yiliang
School of Mechanical Engineering, Taiyuan University of Technology, Taiyuan 030024, China
关键词:
左冠状动脉分叉角度动脉粥样硬化计算流体动力学剪切力壁面压强
Keywords:
Left coronary bifurcation angleAtherosclerosis Computational fluid dynamicsWall shear stressWall pressure
分类号:
R318
DOI:
10.19529/j.cnki.1672-6278.2018.03.10
文献标识码:
A
摘要:
通过个体化正常人体左冠状动脉CT构建不同分叉角度的流体力学模型,应用计算流体动力学(computational fluid dynamics,CFD)的方法模拟研究不同分叉角度左冠状动脉的流体力学特性,从而探讨冠状动脉分叉角度与斑块形成分布的关系。应用有限元仿真模拟并分析不同分叉角度左冠状动脉的流动力学特性。不同分叉角度的冠状动脉在壁面压强(wall pressure,WP)、壁面剪切应力(wall shear stress,WSS)、血液流场分布均存在差异。左冠状动脉分叉模型中存在两处低剪切应力区域:分叉脊附近和分叉对侧。分叉脊附近剪切应力随分叉角度增大而逐渐减小,其范围相应的增大;分叉对侧的低剪切应力及其范围并没有相应的变化。冠状动脉分叉角度与血液流体力学及斑块形成及分布有一定的关系。
Abstract:
To investigate the relationship between the angle of left coronary artery bifurcation and the formation and distribution of plaque by the meanings of the computational fluid dynamics (CFD) technique, based on coronary artery hemodynamics models. Our study revealed that the wall pressure, wall shear stress (WSS) and blood flow pattern of coronary arteries were different in different geometries. There were two regions of low shear stress in the left coronary artery bifurcation model: near the bifurcation ridge and on the opposite side of the bifurcation. The shear stress near the bifurcation ridge decreased with the increasing bifurcation angle, and its range increased correspondingly. However, the low shear stress and its range on the opposite side of the bifurcation had no corresponding change. Our study indicates that the bifurcation of coronary artery is related to blood fluid hemodynamics and the risk of atherosclerosis.

参考文献/References

备注/Memo

备注/Memo:
(收稿日期:2017-10-28) △通信作者Email:wangyiliangwyl@163.com
更新日期/Last Update: 2018-09-30