[1]李俊起,李文明△,王宪鹏,等.一种可释放维生素B2的聚乙烯醇口腔膜的制备及其性能研究*[J].生物医学工程研究,2019,02:227-231.
LI Junqi,LI Wenming,WANG Xianpeng,et al.Preparation and properties of polyvinylalcohol(PVA) oral membrane releasing vitamin B2[J].Journal of Biomedical Engineering Research,2019,02:227-231.
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一种可释放维生素B2的聚乙烯醇口腔膜的制备及其性能研究*(PDF)
《生物医学工程研究》[ISSN:1006-6977/CN:61-1281/TN]
- 期数:
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2019年02期
- 页码:
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227-231
- 栏目:
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- 出版日期:
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2019-06-25
文章信息/Info
- Title:
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Preparation and properties of polyvinylalcohol(PVA) oral membrane releasing vitamin B2
- 文章编号:
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1672-6278 (2019)02-0227 -05
- 作者:
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李俊起; 李文明△; 王宪鹏; 史建华; 朱爱臣; 李博; 郈秀菊; 王传栋
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山东省药学科学院,山东省医用高分子材料重点实验室,济南 250101
- Author(s):
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LI Junqi; LI Wenming; WANG Xianpeng; SHI Jianhua; ZHU Aichen; LI Bo; HOU Xiuju; WANG Chuandong
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Shandong Academy of Pharmaceutical Sciences, Shandong Provincial Key Laboratory of Biomedical Polymers, Jinan 250101, China
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- 关键词:
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维生素B2; 口腔溃疡; 聚乙烯醇; 电纺; 释放
- Keywords:
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Vitamin B2; Oral ulcers; Polyvinylalcohol; Electrostatic spinning; Release
- 分类号:
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R318
- DOI:
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10.19529/j.cnki.1672-6278.2019.02.21
- 文献标识码:
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A
- 摘要:
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本研究将维生素B2溶解于聚乙烯醇(PVA)的水溶液中,利用静电纺丝法制备了含有维生素B2的PVA口腔膜,并测定其理化性能及溶出度。结果表明,该PVA膜具有合适的力学强度,遇水浸泡3 h后的维生素B2含量累计释放度约为85.75%,可以作为贴膜来治疗口腔溃疡。
- Abstract:
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We dispersed vitamin B2 in the solution of PVA and prepared PVA oral membrane containing vitamin B2 by electrostatic spinning method.Its physical and chemical properties and the dissolution rate were determined.The results show that the PVA film has suitable mechanical strength.After soaking in water for 3 h, the release of vitamin B2 was about 85.75%. It can be used as a sticker to treat ulcer surface.
备注/Memo
- 备注/Memo:
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(收稿日期:2019-03-22)山东省重点研发计划项目(2018GSF118132)。△通信作者Email:liwenming1985@163.com
更新日期/Last Update:
2019-07-18