文章摘要

文章信息/Info

作者:: 杨文悦1; 刘肖珩2; 沈阳2; 曾烨2; 陈宇1△; 蒋文涛1; 1. 四川大学生物力学工程省重点实验室，成都 610065；2. 四川大学华西基础医学与法医学院，成都 610041

Author(s):: YANG Wenyue1; LIU Xiaoheng2; SHEN Yang2; ZENG Ye2; CHEN Yu1; JIANG Wentao1; 1.Applied Mechanics，Sichuan University，Chengdu 610065，China;2.West China School of Basic Medical Sciences and Forensic Medicine，Sichuan University，Chengdu 610041

Keywords:: Osteoporosis; Vertebral body; Biomechanics; Fracture; Pedicle screw

摘要:: 随着全球人口老龄化程度日益加剧,骨质疏松症已成为严重威胁社会公共卫生的疾病之一。骨质疏松性椎体压缩骨折是骨质疏松症最常见的并发症。椎弓根螺钉内固定是最常用的骨折固定技术。但骨质疏松骨由于其力学性能发生改变，常规使用的椎弓根螺钉固定无法提供疏松骨所需的稳定性。因此,如何有效地提高骨质疏松条件下椎弓根螺钉的稳定性，是骨质疏松骨折固定方面待解决的首要问题。为了解决该问题,本研究总结了近五年新型骨质疏松椎弓根螺钉的生物力学性能的文献。得出通过改变螺钉轨迹、改用膨胀螺钉、增大插入深度、添加骨水泥等方法可增强椎弓根螺钉固定的稳定性，并在生物相容性材料增强椎弓根螺钉力学性能方面进行展望。

Abstract:: Osteoporosis has become a serious threat to social public health with the increasing aging of the global population. Osteoporotic vertebral compression fracture is the most common complication of osteoporosis. Pedicle screw internal fixation is the most commonly used technique for fracture fixation.However,due to the mechanical properties change of osteoporotic bone, conventional pedicle screw fixation hardly provide the stability required for osteoporosis. Therefore, how to effectively improve the stability of pedicle screw is the primary problem in osteoporotic fracture fixation.In order to solve this problem, we summary the literatures about biomechanical properties of new type of osteoporotic pedicle screws in recent five years,and find the stability of pedicle screw fixation can be enhanced by changing screw trajectory, using expansion screw, increasing insertion depth and adding bone cement.Finally, the application of biocompatible materials in enhancing the mechanical properties of pedicle screws is prospected.