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Title:: A front-end acquisition design for accurate monitoring of noninvasive blood pressure under hypoperfusion

作者:: 王聪1; 肖淑绵2; 王慧泉2; 陈瑞娟2; 何明2; 邢海英1△; （1.天津工业大学电子与信息工程学院，天津 300387；2. 天津工业大学生命科学学院，天津 300387）

Author(s):: WANG Cong1; XIAO Shumian2; WANG Huiquan2; CHEN Ruijuan2; HE Ming2; XING Haiying1; （1.School of Electronic and Information Engineering, TianGong University, Tianjin 300387, China；2.School of Life Sciences, TianGong University,Tianjin 300387）

Keywords:: Noninvasive; Continuous; Blood pressure; Monitoring; Constant volume method; Pulse wave; Low perfusion

摘要:: 本研究针对现有无创血压监测设备采集前端无法实现低灌注信号准确监测的情况，提出一种基于恒定容积法的低灌注血压精确监测的指尖前端采集方案，并基于动物实验，研究了低灌注情况下光电脉搏波及压力脉搏波信号精确采集对血压准确检测的关键影响。6个动物（猪）实验样本的数据分析结果显示，本研究设计的采集前端在低灌注状态下，连续无创血压监测精度可控制在±10 mmHg内，且血压波动追踪相关性大于80%。基于本研究进行低灌注下的无创血压监测在重灾现场、重症临床监护、慢病监护等方面具有重要意义。

Abstract:: Aim at the problem that the acquisition front-end of existing non-invasive blood pressure monitoring equipment cannot achieve accurate monitoring of low perfusion signals, we proposed a fingertip acquisition scheme based on constant volume method for accurate monitoring of blood pressure under low perfusion, and studied the key effects of accurate acquisition of photoelectric pulse wave and pressure pulse wave signal on accurate blood pressure monitoring under low perfusion conditions based on animal experiments.The results showed that the accuracy of continuous non-invasive blood pressure detection at the collection front end in the low perfusion state could be controlled within ±10 mmHg and the correlation of blood pressure fluctuation tracking under low perfusion was > 80%, which were based on the data analysis results of 6 animal (pig) experimental samples. Non-invasive blood pressure monitoring under low perfusion based on this scheme is of great significance in the field of severe disasters, intensive clinical monitoring, and chronic disease monitoring.